PhD Studentship in Computer Science at the University of Surrey, UK

The University of Surrey is looking for a highly motivated candidate for PhD Studentship in Computer Science. The project aims to develop a design space for continuous blending based upon thorough micromechanical analysis of the process. 

Summary

Project Description

Continuous manufacturing is an emerging technology for producing pharmaceutical products. A thorough understanding of material behaviour during the manufacturing process is important in product development and manufacturing. FREEDOM (Enabling scale-flexible process development for continuous solid-dosage manufacturing towards Pharma 4.0) is a consortium funded by VLAIO – Flanders Innovation and Entrepreneurship, Belgium.

Computational modelling will be performed using the discrete element method, and validated using the experimental data to be obtained by other FREEDOM partners. Specific tasks for this project include but not limited to:

• Critical literature review to understand the background, the state-of-the-art and the challenges,  and to identify the knowledge gap.
• Development, calibration and validation of DEM models for continuous powder blending and powder flow in feed frames.

Aims

The project aims to develop a design space for continuous blending based upon thorough micromechanical analysis of the process. Using the design space, optimal process condition can be identified for a given formulation and a required throughput. To achieve this goal, the following specific objectives are identified for this work package:

1. To develop a discrete element model for continuous blending
2. To develop computer models for predicting flow behaviour as a function of formulation properties in the feed frame and during die filling
3. To validate and refine the computer model experimentally to assess the model fidelity
4. To perform a comprehensive numerical analysis of continuous blending, a process regime map can be constructed.

Application Deadline

The deadline for applications is February 28 2021

Eligibility

• We are looking for a highly motivated candidate who holds a master degree or equivalent in engineering, physics or a closely-related discipline, with a keen interest in computer modelling, numerical analysis, particle technology and pharmaceutical engineering.
• The candidate should be a good team player and can engage in interdisciplinary and cross-sectoral collaboration with good oral and written communication skills. 
• Previous experience or some knowledge in discrete element modelling and powder technology is desirable but not essential as training will be provided.
• Overseas students are also welcome to apply.
• IELTS requirements: 6.5 overall with 6.0 in each band or equivalent.

Funding Information

University fees will be covered for students worldwide, with a stipend of £15,009 per annum.

Application Process

Applications should be made through the Chemical and Process Engineering Research PhD course page.

Please contact Professor Charley Wu before submitting to discuss your application.

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